Kinetochore function: molecular motors, switches and gates

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores.1995 · 725 citations
2. 2Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase.1995 · 127 citations
3. 3Kinetochore motility after severing between sister centromeres using laser microsurgery: Evidence that kinetochore directional instability and position is regulated by tension1995 · 133 citations
4. 4Structural and Mechanical Control of Mitotic Progression1991 · 110 citations
5. 5Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis.1996 · 639 citations