Combining ALT/AST Values with Surgical APGAR Score Improves Prediction of Major Complications after Hepatectomy

Figures

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  Figure 1:. Relationship between SAS and postoperative complications. A) Distribution of patients with and without complications across different range of SAS points (0-2, 3-4, 5-6, 7-8, 9-10). Height of the bar indicates percentage of patients. The percentage above bars indicates the ratio of patients with complications after hepatectomy. B) Box and whisker plot representing SAS points of the patients without (−) or with (+) complications after hepatectomy, in which the lines within the box represent median value; the upper and lower lines of the boxes represent the 25th and 75th percentiles respectively; and the upper and lower bars outside box represents the 95th and 5th percentiles respectively. C) Receiver operator characteristic (ROC) curve of SAS points for predicting development of complications after hepatectomy. The calculated area under the curve (AUC) is shown on the graph and the dotted line indicates the best cutoff values (≤6/≥7) with maximum sensitivity and specificity. D) Bar plot representing percentage of patients without (−) or with (+) complications across SAS points cutoff values (≤6/≥7) after hepatectomy.

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  Figure 2:. Increased serum ALT/AST levels as a potential biomarker for postoperative complications. A) Box and whisker plot representing serum albumin, serum AST and serum ALT levels across patients without (−) and with (+) complications after hepatectomy. B) Box and whisker plot representing serum albumin, serum AST and serum ALT levels across different range of SAS points (0-2, 3-4, 5-6, 7-8, 9-10) after hepatectomy. In both plots, the lines within the box represent median value; the upper and lower lines of the boxes represent the 25th and 75th percentiles respectively; and the upper and lower bars outside box represent the 95th and 5th percentiles respectively.