Temperature sensitivity of cyclic adenosine 3':5'-monophosphate-binding proteins and the regulation of growth and differentiation in neuroblastoma cells.

The apparent association constant (K-a) of cAMP to the binding proteins from resistant and nonresistant cells was 7.4 times 10-7 M-1 and 8.2 times 10-7 M-1, respectively, and the specific activity of cAMP BINDING TO THESE PROTEINS WAS SIMILAR FOR BOTH TYPES OF CELLS.