Molekularbiologie der Keimung von Bacillus‐Sporen

The review deals with recent results and problems of gene expression during germination of Bacillus spores. Three problems were selected: The activation of metabolism as a prequisite for the synthesis of nucleic acids and proteins. The activation of nucleic acid and protein synthesis during germination. The gene expression programme of germinating spores. Using the highly sensitive two‐dimensional polyacrylamide gel analysis three major classes of proteins were distinguished, depending on the time of onset and duration of their syntheses: proteins made throughout germination (main class) proteins whose synthesis started only after a lag phase and then continued thoughout germination, and proteins which are synthesized only during the early phases of germination. The programme of protein synthesis is an indicatoir for the control of gene expression during germination. The regulation of expression of these major gene groups during spore outgrowth is discussed.