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March 1, 1990Antimicrobial Agents and ChemotherapyOpen Access

Acute, rapidly progressive renal failure with simultaneous use of amphotericin B and pentamidine

Diana Antoniskis Robert A. Larsen

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Abstract

We report four cases of acute reversible renal failure in patients with acquired immune deficiency syndrome who received both amphotericin B (for systemic mycoses) and pentamidine isethionate (for Pneumocystis carinii pneumonia). The concurrent use of amphotericin B with either inhaled pentamidine or trimethoprim-sulfamethoxazole did not cause significant renal impairment.

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Antoniskis et al. (1990) studied this question.

synapsesocial.com/papers/6a8660e302d24c2587833c66 https://doi.org/10.1128/aac.34.3.470

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