complete medium with limiting amounts of the major energy source, glucose. ' These results suggested that possibly energy metabolism was involved in the control of progression of cells about the cell cycle, and that this control might be ex-Many cell lines grown in tissue culture accumulate in a postmitotic, preDNA-synthetic part of the cell cycle when brought to a nonproliferating state by a variety of techniques (1-5). In our laboratory we have recently shown that a qualitatively
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Chapman et al. (1971) studied this question.
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