A Case of Extensive Calcification in the Brain

Deposits of mineral salts in the brain are found in association with many diseases of the central nervous system. Frequent sites of calcification are tumors originating in the brain and meninges. The deposition of calcium in association with intracranial angiomas, described by Krabbe,¹Eaves²and others, is of especial interest. Such deposits are not uncommon in association with intracranial hematomas; an unusual case of this type was reported recently by Levin.³Calcification in association with encephalitis in man was first described by Buzzard and Greenfield⁴and later by Cobb⁵and others. Da Fano and Perdrau⁶found both pseudocalcification and true deposition of calcium in cases of experimental herpetic meningo-encephalitis in rabbits. Carbon monoxide poisoning may be followed by calcification of the media of arteries within three days.⁷Hurst⁸found deposition of mineral salts in arteries of the basal ganglia in many inflammatory