PVC supported liquid membrane and carbon paste potentiometric sensors incorporating an Mn(III)‐porphyrin complex as a neutral host molecule were developed for the determination of paracetamol. The measurements were carried out in solution at pH 5.5. Under such conditions paracetamol exists as a neutral molecule. The mechanism of molecular recognition between the Mn(III)‐porphyrin and paracetamol, leading to potentiometric signal generation, is discussed.
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Saraswathyamma et al. (2008) studied this question.
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