Long-term administration of interferon resulted in the partial suppression of radiation-induced lymphosarcoma development in strain C57BL mice. The inducer of interferon, polyinosinic acid-polycytidylic acid, was without effect under the same conditions. Interferon also protected C57BL mice against the induction of these tumors by a virus, RadLV, but did not modify the death rate following injection of tumor cells.
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Lieberman et al. (1971) studied this question.