Why the study?
Does rectilinear biphasic cardioversion improve conversion to sustained sinus rhythm in horses with idiopathic sustained atrial fibrillation?
Does rectilinear biphasic cardioversion improve conversion to sustained sinus rhythm in horses with idiopathic sustained atrial fibrillation?
Biphasic electrical cardioversion may provide a safe alternative to pharmacologic cardioversion with quinidine for treating idiopathic atrial fibrillation in horses.
May support biphasic cardioversion safety in equine AF; leaves open comparative efficacy versus quinidine.
Rectilinear biphasic cardioversion was used in 2 horses with idiopathic sustained atrial fibrillation; 1 horse converted to sustained sinus rhythm. Variables that potentially affected outcome of the electrical cardioversion procedures in these horses included duration of arrhythmia, placement of cardioverter pads and paddles, serum electrolyte concentrations, and treatment with quinidine. Serum cardiac troponin I concentration, measured to determine whether the myocardium was damaged from the electrical shocks, was within the reference range in both horses after the procedure. Biphasic electrical cardioversion may provide an alternative to pharmacologic cardioversion with quinidine in horses. The rectilinear biphasic defibrillator-cardioverter uses a unique biphasic waveform to deliver constant current to the myocardium during cardioversion, regardless of transthoracic impedance. Biphasic cardioversion is safer and more effective than traditional monophasic cardioversion in humans and animals.
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Frye et al. (2002) studied this question.
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