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August 2, 2016Biology of Blood and Marrow TransplantationOpen Access

Achieving Molecular Remission before Allogeneic Stem Cell Transplantation in Adult Patients with Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: Impact on Relapse and Long-Term Outcome

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Authors

FLFederico LussanaTITamara IntermesoliFGFrancesca Gianni

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Lussana et al. (2016) studied this question.

synapsesocial.com/papers/6a86918e1d4e7816c90cf9cdhttps://doi.org/10.1016/j.bbmt.2016.07.021
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Imatinib plus steroids induces complete remissions and prolonged survival in elderly Philadelphia chromosome–positive patients with acute lymphoblastic leukemia without additional chemotherapy: results of the Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) LAL0201-B protocol2007 · 376 citations
  2. 2Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome–positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International ALL Trial MRC UKALLXII/ECOG29932009 · 287 citations
  3. 3Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL2012 · 474 citations
  4. 4Dasatinib as first-line treatment for adult patients with Philadelphia chromosome–positive acute lymphoblastic leukemia2011 · 465 citations