Why the study?
Do patients with rheumatoid arthritis have a higher prevalence of autonomic neuropathy compared to age-matched controls?
Do patients with rheumatoid arthritis have a higher prevalence of autonomic neuropathy compared to age-matched controls?
Autonomic neuropathy is significantly more common in patients with rheumatoid arthritis than previously suspected, which may contribute to increased morbidity and mortality.
May support autonomic evaluation in RA; case-control data leaves open impact on outcomes.
Patients with seropositive and seronegative rheumatoid arthritis (RA) and age-matched controls were investigated for the presence of autonomic neuropathy. Significantly more patients with RA had abnormal autonomic function, suggesting that autonomic neuropathy occurs more commonly in RA than hitherto suspected. The existence of an autonomic neuropathy may be an important complicating factor in rheumatoid disease and may lead to increased morbidity and mortality.
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Edmonds et al. (1979) studied this question.
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