THE tremendous advances made in drug therapy in the past decade have created considerable confusion in the minds of many. Most of the new medicinal agents have undoubtedly contributed much to the physician's ability to treat his patients better. Unfortunately, the appearance of new substances has been so rapid as to keep anyone from being able to understand them fully and to evaluate them wisely, much less to employ them with skill in the treatment of the patient.Around the turn of the century, Osler and other medical leaders were seriously concerned about the profusion of what seemed to them . . .
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Friend et al. (1956) studied this question.
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