2-Trifluoromethylated Indoles via Radical Trifluoromethylation of Isonitriles

Either two or three C-C bonds are formed in the synthesis of 2-trifluoromethylindoles starting with readily prepared isonitriles and the Togni reagent as CF3 radical precursor. These transformations occur in the absence of transition metal, and products are obtained in moderate to good yields with excellent diastereoselectivity.