Why the study?
Does low-dose aspirin or NSAIDs reduce hospital mortality in patients with severe sepsis or septic shock?
Population
979 patients with severe sepsis or septic shock
Design
Cohort
Authors
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Hypothesis-generating for mortality benefit from aspirin or NSAIDs in sepsis; does not support combined use or practice change.
Does low-dose aspirin or NSAIDs reduce hospital mortality in patients with severe sepsis or septic shock?
Low-dose aspirin or NSAIDs may decrease hospital mortality in severe sepsis or septic shock, but not when used in combination.
Soßdorf et al. (2012) studied this question.
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