Split-and-mix libraries are an excellent tool for the identification of peptides that induce the formation of Ag nanoparticles in the presence of either light or sodium ascorbate to reduce Ag(+) ions. Structurally diverse peptides were detected in colorimetric on-bead screenings that generate Ag nanoparticles of different sizes, as confirmed by SEM and X-ray powder diffraction studies.
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Belser et al. (2009) studied this question.
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