Magnesium's role in muscle contraction biochemistry warrants targeted cardiac studies; leaves open any clinical relevance in humans.
The evidence is now strong that magnesium plays an important role in the interactions between myosin, actin and ATP which are associated with the physiological activity of muscle. Although cal- cium activates the adenosine triphosphatase ofboth L-myosin and isolated myofibrils, in the presence of this cation alone neither contraction (Ashley,
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Leadbeater et al. (1963) studied this question.
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