Key result
An additional Hib vaccine dose given before one year of age to infants with low primary responses was evaluated for antibody persistence, though results are truncated.
Why the study?
Does an early booster dose of Hib vaccine improve the persistence of Hib IgG titres in infants with low primary responses?
Observational
Does an early booster dose of Hib vaccine improve the persistence of Hib IgG titres in infants with low primary responses?
This study evaluates the long-term persistence of Hib antibodies following an early booster dose in infants with poor initial vaccine responses.
Answers are grounded in this paper and cite their sources.
Early Hib booster in low responders should not yet alter schedules; leaves open long-term persistence benefit pending randomized data.
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M H Slack (2005) conducted an observational in Haemophilus influenzae type b (Hib) immunity. Additional Hib vaccine dose was evaluated on Persistence of Hib IgG response. An additional Hib vaccine dose given before one year of age to infants with low primary responses was evaluated for antibody persistence, though results are truncated.
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