The Therapeutic Use of Venesection in Polycythemia

Article1 April 1937THE THERAPEUTIC USE OF VENESECTION IN POLYCYTHEMIAD. J. STEPHENS, M.D., NOLAN L. KALTREIDER, M.D.D. J. STEPHENS, M.D.Search for more papers by this author, NOLAN L. KALTREIDER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-10-10-1565 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough venesection has been used for many years as an emergency measure in erythremia, its general use as a therapeutic agent in this disease has been considered contraindicated on the grounds that reduction of the blood level by this means would act as a further stimulus to erythrocyte production.1Recent investigations, however, have indicated that this assumption may be unwarranted. Falconer2has shown that the repeated removal of from 200 to 600 c.c. of blood at intervals of from a few days to three weeks did not increase the reticulocyte percentage above normal limits. Reimann and Breuer3have studied the...Bibliography1. HARROP GA(a) : Polycythemia, Medicine, 1928, vii, 291. (b) PARK, G. T., and CRAVER, L. F.: The radiation therapy of polycythemia vera, Am. Jr. Med. Sci., 1930, clxxx, 609. (c) FORKNER, C. E., SCOTT, T. F., and WU, S. C.: Treatment of polycythemia vera with solution of potassium arsenite, Arch. Int. Med., 1933, li, 616. Google Scholar2. FALCONER EH: Treatment of polycythemia. The reticulocyte response to venesection, phenylhydrazine and radiation, ANN. INT. MED., 1933, vii, 172. LinkGoogle Scholar3. REIMANNBREUER FA: Die Aderlassbehandlung der Erythrämie, Ztschr. f. klin. Med., 1935, cxxviii, 238. Google Scholar4. GIFFINCONNER HZHM: The untoward effects of treatment by phenylhydrazine hydrochloride, Jr. Am. Med. Assoc., 1929, xcii, 1505. 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PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPolycythemia Vera: Scientific Advances and Current PracticePolycythemia vera: myths, mechanisms, and managementTHE OPTIMAL MANAGEMENT OF POLYCYTHAEMIA VERA4 Treatment of polycythaemia vera and essential thrombocythaemiaPolycythemiaErythrocythemiaPolycythaemia veraPOLYCYTHÆMIA VERAThe treatment of polycythemia veraBehandlung der Polycythaemia vera mit DaraprimTreatment of Polycythemia Vera with large Venesections and Plasma Transfusions.Die Erkrankungen des erythrocytären Systems 1 April 1937Volume 10, Issue 10Page: 1565-1581KeywordsBloodDentistryHospital medicinePhlebotomyPolycythemiaPolycythemia veraReticulocytes ePublished: 1 December 2008 Issue Published: 1 April 1937 PDF downloadLoading ...