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This paper serves as an introduction to a discussion meeting issue reviewing the history, structure, and function of myosin and the sliding-filament model of muscle contraction.
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This historical and scientific review outlines the evolution of our understanding of muscle contraction, from the discovery of sarcomeres to the detailed molecular mechanics of the myosin crossbridge cycle.
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Holmes et al. (2004) conducted an editorial in Muscle contraction and myosin function. This paper serves as an introduction to a discussion meeting issue reviewing the history, structure, and function of myosin and the sliding-filament model of muscle contraction.
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