Key result
Serum sickness following tetanus antitoxin injection triggers acute myocardial infarction in a young adult.
Why the study?
Myocardial infarction during serum sickness has been reported but remains a rare and poorly characterized clinical occurrence.
Case Report (n=1)
Highlights a rare case of myocardial infarction occurring during serum sickness in an otherwise healthy young man.
Answers are grounded in this paper and cite their sources.
Serum sickness may rarely trigger MI in young adults without cardiac risks; hypothesis-generating case report leaves causal link open.
Myocardial infarction during serum sickness has been reported several times.In the following case the patient was a young man with no other evidence of heart disease and no family history of coronary disease.Case Report A bus-fitter, aged 36 years, was given tetanus antitoxin for a cut finger; a similar injection had been received twelve years previously without reaction.Seven days later a general urticarial rash appeared, and two hours later he felt faint and fell to his knees.He went to bed and slept for six hours, waking with pruritus and mild precordial pain; after a subcutaneous injection of adrenaline the pain became more intense and radiated to the left arm.On admission to Crumpsall Hospital one hour later, he had general urticaria, and profuse sweating, and was suffering constricting prvcordial pain of a severity requiring morphine.There were no abnormal
No takes yet. Share an insight, caveat, or question.
N. J. Roussak (1954) conducted a case report in Myocardial infarction during serum sickness (n=1). Tetanus antitoxin was evaluated on Myocardial infarction. A 36-year-old man with no prior cardiac history developed a myocardial infarction during serum sickness seven days after receiving a tetanus antitoxin injection.
Synapse has enriched 10 related papers. Consider them for comparative context: