Rehabilitated: The rhodium-catalyzed allylic alkylation is indeed a viable alternative to the better-known palladium-catalyzed version. Rhodium complexes show a different regioselectivity and have a low tendency for isomerization. The allylations proceed with excellent chirality transfer for both branched and linear products (see scheme; Tfa=trifluoroacetyl).
No takes yet. Share an insight, caveat, or question.
Kazmaier et al. (2006) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: