Answers are grounded in this paper and cite their sources.
The management of musculoskeletal infections is an increasing challenge to clinicians. Bioimplants provide a unique system for skeletal specific drug delivery. Antibiotic-impregnated beads and spacers can be used to treat chronic osteomyelitis and deep soft-tissue infections locally with higher antibiotic concentrations, while avoiding potential systemic side effects.
No takes yet. Share an insight, caveat, or question.
Wang et al. (2002) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: