The present study provides a thorough assessment of the cream formulation, combining various physical, chemical, and toxicological analyses to determine its quality, stability, and safety for topical application. The investigation evaluated important parameters such as color, odor, and texture, confirming a consistent and visually acceptable physical profile maintained over 16 weeks. Other assessments, such as washability, phase separation, and pH measurements within the skin's natural range (5–7), further validate the formulation's stability and user compatibility. Safety evaluations using patch tests and toxicology studies employing albino mice showed no signs of skin irritation or systemic toxicity, which is in accordance with accepted practices in cosmetic research. A thorough chemical characterization was given by the FTIR analysis, which also identified an extra quinone group that was caused by the addition of turmeric and Aloe Vera in addition to the usual functional groups (ether, phenolic, and aldehyde). This new discovery supports previous research on the effectiveness of botanical additives in cosmetic formulations by indicating increased bioactivity and better product qualities.
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IK et al. (2025) studied this question.
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