Critically Safe General Anaesthesia in Closed Loop: Availability and Challenges

This paper provides an up-to-date review of intersecting know-how in engineering, medical and computer science frameworks. The text interweaves available measures, models, controls and technology for drug delivery systems in general anesthesia. The three main actors, equally important, along with their role in overall performance are presented and analyzed from a global perspective. The availability of patient information for personalized healthcare is systematically analyzed and the possibility to integrate this hybrid information sources into personalized patient models are critically sought. Finally, an important role is given to the accurate, crisp and real-time information availability in medical devices. Modular integration of new items is of paramount importance in terms of space, computational burden and number of training hours.