OBJECTIVE: To see whether a cholinomimetic medication would help resolve the parotid gland enlargement associated with self-induced vomiting in bulimic patients. SETTING/DESIGN: The medication was administered on an inpatient eating disorder unit to bulimic patients with refractory sialadenosis. INTERVENTION: Pilocarpine hydrochloride drops were administered orally at a dosage of 1.25 to 5.0 mg/d until the parotid gland enlargement was significantly reduced. RESULTS: There was a marked diminution in the size of the parotid gland enlargement. CONCLUSION: Pilocarpine has proved to be beneficial in the treatment of sialadenosis in bulimic patients.
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Mehler et al. (1993) studied this question.
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