Key result
Subjects experiencing dizziness upon standing showed a significantly greater drop ratio in cephalic blood flow (0.62 vs 0.55, P=0.023) and systolic blood pressure compared to those without dizziness.
Why the study?
Can a new wearable cephalic laser blood flowmeter accurately detect hemodynamic changes associated with orthostatic dizziness during postural changes in healthy volunteers?
Cross-Sectional (n=63)
No
Can a new wearable cephalic laser blood flowmeter accurately detect hemodynamic changes associated with orthostatic dizziness during postural changes in healthy volunteers?
A novel wearable cephalic laser blood flowmeter can effectively detect transient decreases in cephalic blood flow that correlate with systolic blood pressure drops and orthostatic dizziness upon standing.
Wearable cephalic flow monitoring correlates with orthostatic dizziness; hypothesis-generating and should not yet change clinical practice.
BACKGROUND: Patients with orthostatic hypotension have pathologic hemodynamics related to changes in body posture. A new cephalic laser blood flowmeter that can be worn on the tragus to investigate the hemodynamics upon rising from a sitting or squatting posture was developed. METHODS AND RESULTS: The relationship between cephalic hemodynamics and cerebral ischemic symptoms in 63 subjects in a sitting, squatting, and standing positions using the new device was evaluated. Transient decrease in blood pressure within 15 s after rising to an erect position possibly causes dizziness, syncope, and fall. Subjects exhibiting dizziness upon standing showed a significant decrease in the cephalic blood flow (CBF) and indirect beat-to-beat systolic blood pressure, as monitored by the Finometer, and a significant correlation was observed between the drop ratio (drop value on rising/mean value in the squatting position) of CBF and that of systolic blood pressure. CONCLUSIONS: This new wearable CBF-meter is potentially useful for estimating cephalic hemodynamics and objectively diagnosing cerebral ischemic symptoms of subjects in a standing posture.
No takes yet. Share an insight, caveat, or question.
Fujikawa et al. (2009) conducted a cross-sectional in Healthy volunteers (evaluating orthostatic dizziness) (n=63). Postural change (squatting to standing) vs. Non-dizziness group was evaluated on Drop ratio of cephalic blood flow (CBF) upon rising to an erect position (p=0.023). Subjects experiencing dizziness upon standing showed a significantly greater drop ratio in cephalic blood flow (0.62 vs 0.55, P=0.023) and systolic blood pressure compared to those without dizziness.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: