Systemic Treatment of Creeping Eruption

IN THE time-honored but, unfortunately, always awkward and frequently unsatisfactory treatment of larva migrans as encountered in this country, various physical and chemical local applications have been employed. Since the classic delineation of this condition as seen in the southeastern United States by Kirby-Smith, Dove and White 1 in 1926, there had been no radical changes in its therapy until D. C. Smith 2 introduced the use of fuadin in 1943. Following this real advance in therapeutics, reports have appeared which in the main substantiate the observation that this antimony compound is in many instances toxic for the larva (Wilson 3 and Rubin 4 ). However, some investigators have found that the medicament is frequently ineffective in completely eradicating the infestation (Blank 5 and Dolce and Franklin 6 ). Recently Hailey and Hailey 7 reverted to local therapy after becoming discouraged with the use of fuadin systemically and reported cures with the