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Two patients who underwent extensive pre‐operative skin preparations with Hibiscrub prior to orthopaedic operations developed acute contact dermatitis at the operation site post‐operatively, Both were shown to be sensitised to Ammonyx LO, the foaming agent in Hibiscrub, and one also to chlorliexidine diglcomate. The details of two other patients who had reacted similary were reviewed.
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Roberts et al. (1981) studied this question.
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