In reviewing the literature of poison ivy dermatitis one observes contradictory trends of opinion on various phases of the subject. The nature of the process is in question. Is it merely a contact dermatitis or a manifestation of allergy ? Vaughan¹expressed the thought that poison ivy dermatitis is probably not allergic. Coca and Grove,²using the Prausnitz-Küstner test, failed to demonstrate sensitizing bodies in the blood of persons sensitive to poison ivy. Rostenberg and Sulzberger³stated that the result of a patch test is much more liable to be positive in contact dermatitis than in the atopic variety. Spain and Cooke⁴concluded that sensitization is transmitted from the original focus to other parts of the skin and mucous membranes by the blood and lymph. Recently Straus and Coca,⁵after experimentation on rhesus monkeys decided that sensitization develops only in connected skin by continuity, and hence,
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FRANK CROZER KNOWLES (1938) studied this question.