An efficient and atom-economic method for the synthesis of multisubstituted indolizines via gold-catalyzed cascade hydroarylation/cycloaromatization reaction of α-(N-pyrrolyl)ketones with alkynes is described. The reaction is realized through the construction of the pyridine ring of indolizines, which allows the regioselective incorporation of a wide range of functionalities on the pyridine unit.
No takes yet. Share an insight, caveat, or question.
Li et al. (2016) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: