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Direct alkylation of a methyl group, on di‐ and trisubstituted ureas, with terminal alkenes by C(sp 3 )−H bond activation proceeded in the presence of a hydroxoiridium/bisphosphine catalyst to give high yields of the corresponding addition products. The hydroxoiridium/bisphosphine complex generates an amidoiridium intermediate by reaction with ureas having an N−H bond.
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Yamauchi et al. (2017) studied this question.
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