Antireceptor-Antibody Decline Without Improvement After Plasmapheresis in Myasthenia Gravis

Letters and Corrections1 May 1980Antireceptor-Antibody Decline Without Improvement After Plasmapheresis in Myasthenia GravisTERRENCE L. RILEY, M.D., W. P. MONAGHAN, PH.D.TERRENCE L. RILEY, M.D.Search for more papers by this author, W. P. MONAGHAN, PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-92-5-713_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Plasma exchange has become an accepted form of treatment for myasthenia gravis since Pinching and Peters first reported this approach in 1976 (1). Several studies have suggested that the clinical improvement after plasma exchange is due to a drop in circulating antireceptor antibody (2, 3). We recently treated by plasma exchange a myasthenic patient in whom a significant decline in antireceptor antibody was not accompanied by any clinical improvement.A 37-year-old woman had been treated for myasthenia for 10 years. Early in the course of her disease, a malignant thymoma had been removed via trans-sternal approach, and...References1. PINCHINGPETERS AD. Remission of myasthenia gravis following plasma exchange. Lancet. 1976;2:1373-6. CrossrefMedlineGoogle Scholar2. DAULINDSTROMCASSELDENYSSHEVSPITLER PJCEEL. Plasmapheresis and immunosuppressive therapy in myasthenia gravis. N Engl J Med. 1977;297:1134-40. CrossrefMedlineGoogle Scholar3. NEWSOM-DAVISPINCHINGVINCENTWILSON JAAS. Function of circulating antibody to acetylcholine receptor in myasthenia gravis: investigation by plasma exchange. Neurology (Minneap). 1978;28:266-72. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByPlasmapheresis in Myasthenia Gravis. A surveyPlasmaexchange in Myasthenia GravisMyasthenia gravisEffect of prethymectomy plasma exchange on postoperative respiratory function in myasthenia gravisPlasma Exchange in Neurological Diseases: A Critical Approach 1 May 1980Volume 92, Issue 5Page: 713-713KeywordsBlood plasmaMyasthenia gravisThymoma Issue Published: 1 May 1980 PDF DownloadLoading ...