Electrolytes and Enzymes Variations in Diabetic Keto Acidosis

Objective: This study aims to evaluate the levels of serum electrolytes and enzymes in diabetic ketoacidosis compared with age matched healthy control population. Method: Cross sectional study involving 94 individuals above the age 60 years in the population of Bengaluru, India between October 2017 to November 2019.Venous blood was collected from 47 type 2 diabetic ketoacidosis patients and from 47 healthy individuals and analyzed for sodium, chloride, potassium, phosphorous electrolytes and serum amylase and lipase enzymes. Results: Serum sodium, potassium and chloride levels were significantly low while serum phosphorous, amylase and lipase levels were significantly high compared to healthy control population. Conclusion: Frequent monitoring of these electrolytes and enzymes in mild stage of diabetic ketoacidosis may help in better treatment and thereby preventing it from progressing into severe diabetic ketoacidosis.