Key result
Percutaneous mechanical thrombectomy significantly improved thrombus clearance rate, pulmonary artery pressure, and hospitalization time compared to catheter-directed thrombolysis in patients with moderate and high-risk acute pulmonary embolism.
Why the study?
The study was conducted to compare the efficacy of PMT and CDT in moderate and high-risk APE and explore the clinical application value of serum biomarkers in this setting.
Does percutaneous mechanical thrombectomy improve thrombus clearance and hemodynamics compared to catheter-directed thrombolysis in patients with moderate and high-risk acute pulmonary embolism?
Population
84 patients with moderate and high-risk APE
Comparison
PMT vs CDT
Design
Two-centre comparative study
Follow-up
Half a year
Authors
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May guide PMT versus CDT selection in moderate-high risk APE; leaves open biomarker validation in randomized trials.
Cohort (n=84)
Yes
Does percutaneous mechanical thrombectomy improve thrombus clearance and hemodynamics compared to catheter-directed thrombolysis in patients with moderate and high-risk acute pulmonary embolism?
p-value: p=0.04
Percutaneous mechanical thrombectomy offers superior thrombus clearance, faster effective thrombolytic time, and reduced hospital stay compared to catheter-directed thrombolysis in moderate and high-risk acute pulmonary embolism.
Guan et al. (2023) conducted a cohort in Acute pulmonary embolism (n=84). Percutaneous mechanical thrombectomy vs. Catheter-directed thrombolysis was evaluated on Thrombus clearance rate (p=0.04). Percutaneous mechanical thrombectomy significantly improved thrombus clearance rate, pulmonary artery pressure, and hospitalization time compared to catheter-directed thrombolysis in patients with moderate and high-risk acute pulmonary embolism.
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