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January 1, 1998Chemical Communications

β-Lactam synthetase: implications for β-lactamase evolution

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Abstract

A synthetase enzyme catalyses formation of the monocyclic β-lactam ring during clavulanic acid biosynthesis.

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Cite This Study

McNaughton et al. (1998) studied this question.

synapsesocial.com/papers/6a87011b240d988a48a244e2 https://doi.org/10.1039/a806713i

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Probing the Mechanism of Nitrogen Transfer in <i>Escherichia coli</i> Asparagine Synthetase by Using Heavy Atom Isotope EffectsOriginal Research · 1996 · 33 citations
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4Chemistry and biosynthesis of clavulanic acid and other clavamsOriginal Research · 1997 · 143 citations
5Glutamine-dependent nitrogen transfer in Escherichia coli asparagine synthetase B. Searching for the catalytic triad.Original Research · 1994 · 69 citations