Key result
Among 42 pregnant women with cardiac disease, the case fatality rate was 9.52%, primarily caused by respiratory failure, sepsis, and cardiogenic shock.
Why the study?
Cardiovascular alterations in pregnancy and pregnancy-related heart disease increase morbidity and mortality risks, prompting characterization of affected pregnant women at this center.
Observational (n=42)
No
In a single-center Indonesian cohort, pregnant women with cardiac disease had a prevalence of 2.68% and a case fatality rate of 9.52%, highlighting the significant morbidity and mortality risk in this population.
Introduction: Increased cardiac output, decreased systemic vascular resistance, and left ventricular hypertrophy are among the cardiovascular alterations brought on by pregnancy.Pregnancy-related heart problems can increase the risk of morbidity and death in both the mother and the newborn.The aim of this research is to characterizing the characteristics of pregnant women with heart disease patients in RSUP Prof. Dr. I.G.N.G.Ngoerah, Denpasar, Indonesia.Methods: This research is included in the type of retrospective descriptive research using medical record data at this hospital from 1 January 2020 to 31 December 2021 with a total sampling method.Inclusion criteria include all cardiac disease in pregnancy cases.Cases with incomplete data were excluded.Data were subsequently analyzed with SPSS 26th edition.Results: There were 46 cases of cardiac disease in pregnancy recorded and 4 cases were excluded.The prevalence in pregnancy was 2.68%.The characteristics of most of the cases were in 20-35 years old group (71.4%), high school graduates (69.0%), normal body mass index (38.1%),multigravida (64.3%), diagnosed at ≥37 gestational age (52.4%), booked case (85.7%), with known previous cardiac disease (54.8%), diagnosed with congenital heart disease (23.8%),WHO class IV (33.3%), underwent cesarean section (71.4%), birth weight <2,500 gram (52.4%), vigorous baby (71.4%), used IUD as postpartum contraception (45.2%), hospitalized in intensive ward after delivery (52.4%) and length of stay were 5-10 days (45.2%).There were 4 maternal mortality cases with case fatality rate (CFR) of 9.52% caused by respiratory failure, sepsis and cardiogenic shock.Discussion: There was a slight increase in prevalence and decrease of CFR of cardiac disease in pregnancy in our hospital compared to previous data in 2016-2017 which may cause by better referral system and patient care. Conclusion:In general, the characteristics of patients in our study were similar to previous studies in developing countries.
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Wiradnyana et al. (2025) conducted an observational in Cardiac disease in pregnancy (n=42). Cardiac disease was evaluated on Maternal mortality (case fatality rate). Among 42 pregnant women with cardiac disease, the case fatality rate was 9.52%, primarily caused by respiratory failure, sepsis, and cardiogenic shock.
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