With the development of sequencing techniques, a growing number of data has been generated, especially the sequencing data. "Big data era" is a coined term from the internet and computer science. However, it is also popular in the bioinformatics researches due to the big scholar fundings, such as Human Genome Program, Human Microbiome Project, 1000 Genomes, etc. We would like to discuss the bioinformatics big data problems, and share some of our comments and perspectives.
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Guo et al. (2019) studied this question.
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