A phosphodiesterase with a low Michaelis constant for cyclic adenosine monophosphate was found in the membrane fraction of the cellular slime mold. This activity was highest during the aggregation stage. Enzyme with similar properties was also secreted by the cells. Dithiothreitol inhibited both enzymes and potentiated the cellular response to cyclic adenosine monophosphate.
No takes yet. Share an insight, caveat, or question.
Pannbacker et al. (1972) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: