A case is presented of widely metastasizing carcinoid tumor with clinical manifestations of the carcinoid syndrome arising in an adult cystic ovarian teratoma in a 66-year-old woman. Biochemical assays showed both 5-HIAA and calcitonin levels to be markedly elevated. By light microscopy, the neoplasm was strongly argyrophilic and weakly argentaffin positive. Ultrastructurally, the presence of pleomorphic intracellular dense core granules averaging 260 nm in diameter were found. The literature is reviewed.
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Sens et al. (1982) studied this question.
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