Key result
A 73-year-old male on steady anticoagulation therapy experienced recurrent intracerebral hemorrhages, highlighting the need to consider alternative etiologies such as paraneoplastic syndrome.
Why the study?
Managing cerebral hemorrhage in patients requiring anticoagulant therapy is a therapeutic challenge, lacking convincing guidelines, and requires considering causes beyond anticoagulation alone.
Case Report (n=1)
Highlights the importance of considering alternative etiologies, such as paraneoplastic syndromes from lung cancer, in patients with recurrent cerebral hemorrhage on anticoagulant therapy.
Consider alternative etiologies in anticoagulated patients with cerebral hemorrhage; case report leaves optimal strategy open for prospective study.
Cerebral hemorrhage management in a patient requiring anticoagulant therapy is a therapeutic challenge also due to the absence of guidelines that convincingly define the best therapeutic strategy. Although the occurrence of cerebral hemorrhage in a patient with anticoagulant therapy seems to make the bleeding etiology obvious, sometimes, it is better to reflect on other possible causes and set up an adequate diagnostic workup. Herein, we describe a case of a 73-year-old male patient with atrial fibrillation, mechanical heart valve, and pacemaker that experienced an ischemic minor stroke during steady anticoagulation therapy with recurrent intracerebral haemorrhages (ICHs).
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Alessiani et al. (2023) conducted a case report in Recurrent intracerebral hemorrhages in a patient with lung cancer, atrial fibrillation, and mechanical heart valve (n=1). Anticoagulant therapy was evaluated on Recurrent intracerebral haemorrhages. A 73-year-old male on steady anticoagulation therapy experienced recurrent intracerebral hemorrhages, highlighting the need to consider alternative etiologies such as paraneoplastic syndrome.
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