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May 27, 2020Journal of the Egyptian National Cancer InstituteOpen Access

Report of two rare cases of adrenal incidentalomas with different origins: revisiting pathological and radiological findings with a short review of the literature

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Key result

Surgical management of rare primary adrenal incidentalomas, including angiosarcoma and diffuse B-cell lymphoma, resulted in disease-free survival at 6 months to 3 years of follow-up.

Why the study?

Rare histopathological findings in incidentally detected adrenal tumors are uncommon, prompting the need to identify their clinical characteristics, management, and post-treatment outcomes.

Population

Two patients with rare primary adrenal tumors initially diagnosed as incidentalomas

Design

Case report

Authors

MEM. A. ElbasetMZMohamed H. ZahranMBMohamed Badawy

Discussion

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Overview

Rare adrenal incidentalomas extend the differential in imaging-detected masses; leaves open standardized management and outcomes data.

Study Design

Type

Case Report (n=2)

Multicenter

No

Structured PICO

P
Population
Two patients, a 52-year-old man and a 63-year-old woman, with incidentally discovered rare primary adrenal tumors (angiosarcoma and diffuse B-cell lymphoma) managed surgically.
I
Intervention
Adrenalectomy (with adjuvant CHOP chemotherapy for the lymphoma case)
O
Outcome
Clinical outcomes after treatment (disease-free survival)hard clinical

Rare primary adrenal tumors such as angiosarcoma and lymphoma can present as incidentalomas and be successfully managed with adrenalectomy and appropriate adjuvant therapy.

Limitations

  • Case report design with only two patients limits generalizability
  • Rarity of the condition makes large-scale studies difficult

Cite This Study

Elbaset et al. (2020) conducted a case report in Adrenal incidentalomas (n=2). Adrenalectomy was evaluated on Clinical outcome after treatment. Surgical management of rare primary adrenal incidentalomas, including angiosarcoma and diffuse B-cell lymphoma, resulted in disease-free survival at 6 months to 3 years of follow-up.

synapsesocial.com/papers/6a87146624dcec08efbf0567https://doi.org/10.1186/s43046-020-00039-z
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic factors in angiosarcoma: A multivariate analysis of 55 cases1996 · 206 citations
  2. 2Molecular pathogenesis of primary central nervous system lymphoma2006 · 45 citations
  3. 3The collection of five interesting cases of adrenal tumors from one medical center2014 · 13 citations
  4. 4Hormonal activity in clinically silent adrenal incidentalomas2012 · 20 citations