September 24, 2012European Heart Journal

Safety of provocative tests of coronary artery spasm and prediction of long-term outcome: need for an innovative clinical research strategy

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Why the study?

Are provocative tests of coronary artery spasm safe and predictive of long-term outcomes in patients with vasospastic angina?

Structured PICO

Are provocative tests of coronary artery spasm safe and predictive of long-term outcomes in patients with vasospastic angina?

Population

1246 patients with angiographically documented vasospastic angina (VSA)

Intervention

Provocative tests of coronary artery spasm (CAS)

Outcome

Major acute cardiac events (MACEs) and arrhythmic risksafety

Limitations

Largely retrospective
Incomplete clinical characterization of patients (no information on onset, duration, and severity of symptoms)

Discussion

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Implication

Provocative testing for coronary artery spasm has a low acute arrhythmogenic risk and low long-term MACE risk, highlighting the need for innovative research strategies to identify specific predictors of life-threatening events.

Cite This Study

Attilio Maseri (2012) studied this question.

synapsesocial.com/papers/6a8718f1854ced5b0ecf7f16 https://doi.org/10.1093/eurheartj/ehs312

View Full Paper

Ask AI

Bookmark

Safety of provocative tests of coronary artery spasm and prediction of long-term outcome: need for an innovative clinical research strategy

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Safety of provocative tests of coronary artery spasm and prediction of long-term outcome: need for an innovative clinical research strategy

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Also Consider