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January 1, 2006Circulation JournalOpen Access

Utility of Second Derivative of the Finger Photoplethysmogram for the Estimation of the Risk of Coronary Heart Disease in the General Population

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Why the study?

Does the second derivative of the finger photoplethysmogram (SDPTG) correlate with the Framingham risk score and identify high-risk subjects for CHD in the general population?

Population

211 subjects from a community in Yamanashi, Japan, without apparent atherosclerotic disorders, renal…

Design

Cross-sectional

Authors

TOToshiaki OtsukaInterventional / Structural CardiologyTKTomoyuki KawadaNippon Medical School HospitalMKMasao KatsumataNippon Medical School

Discussion

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Implication

b/a index may aid CHD risk estimation in general populations; leaves open clinical adoption without prospective validation.

Structured PICO

Does the second derivative of the finger photoplethysmogram (SDPTG) correlate with the Framingham risk score and identify high-risk subjects for CHD in the general population?

P
Population
211 subjects (age: 63±15 years, range: 21–91 years, 93 males) from a community in Yamanashi, Japan, without apparent atherosclerotic disorders, renal dysfunction, or medications for hypertension, hyperlipidemia, or diabetes mellitus.
I
Intervention
Measurement of the second derivative of the finger photoplethysmogram (SDPTG) indices (b/a and d/a)
O
Outcome
Correlation between SDPTG indices and the Framingham risk score, and discrimination of high-risk subjects for CHDsurrogate

The SDPTG index b/a correlates with the Framingham risk score and may serve as a useful, non-invasive screening tool for estimating CHD risk in the general population.

Limitations

  • None of the subjects with diabetes participated
  • Cross-sectional survey, so it is uncertain if SDPTG truly predicts mortality and morbidity from CHD
  • Small number of subjects, particularly males, which might have resulted in lower specificity

Cite This Study

Otsuka et al. (2006) studied this question.

synapsesocial.com/papers/6a8726cc24dcec08efbf095ehttps://doi.org/10.1253/circj.70.304
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Also Consider

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