Since vancomycin-resistant enterococci (VRE) were first isolated in Europe, rates of VRE colonization and infection have risen steadily. Today VRE have emerged as important nosocomial pathogens worldwide; hence, it is crucial to understand the underlying mechanism in the spreading of VRE. This article reviews the mechanism of resistance to vanco-mycin and global epidemiology of VRE, as well as the current molecular techniques that are being ap-plied to the epidemiological studies of VRE.
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Wee Gyo Lee (2008) studied this question.
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