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August 1, 2013Cell ReportsOpen Access

A Role for Angiopoietin-2 in Organ-Specific Metastasis

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Editorial

Authors

NRNicolò RigamontiVita-Salute San Raffaele University MPMichele De PalmaGoethe University Frankfurt

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Implication

Highlights the role of the calcineurin-NFAT pathway and ANG2 as potential targets for inhibiting pulmonary tumor metastasis.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Rigamonti et al. (2013) studied this question.

synapsesocial.com/papers/6a87362cd75f6552a082c04d https://doi.org/10.1016/j.celrep.2013.07.034

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Hypoxia and Vascular Endothelial Growth Factor Selectively Up-regulate Angiopoietin-2 in Bovine Microvascular Endothelial Cells1999 · 495 citations
2Angiopoietin-2 promotes myeloid cell infiltration in a β2-integrin–dependent manner2011 · 100 citations
3Effects of Angiopoietin-2-Blocking Antibody on Endothelial Cell–Cell Junctions and Lung Metastasis2012 · 217 citations
4Angiopoietin-2: An Attractive Target for Improved Antiangiogenic Tumor Therapy2013 · 205 citations
5The Calcineurin-NFAT-Angiopoietin-2 Signaling Axis in Lung Endothelium Is Critical for the Establishment of Lung Metastases2013 · 115 citations