Why the study?
Aortic compliance is often estimated assuming negligible longitudinal stretch, but the proximal aorta undergoes significant axial stretch during cardiac contraction.
Does accounting for longitudinal stretch improve the estimation of proximal aortic wall compliance compared to neglecting it?
Population
3 healthy young volunteers and a 3-D finite element model of the proximal aorta
Comparison
Actual wall compliance vs compliance estimated neglecting longitudinal stretch
Design
In silico computational and in vivo MRI study
Authors
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May refine aortic compliance estimates in research models; leaves open need for clinical method adjustments.
Does accounting for longitudinal stretch improve the estimation of proximal aortic wall compliance compared to neglecting it?
Neglecting longitudinal strain during cardiac contraction can lead to severe underestimation of local aortic compliance, especially in subjects with high aortic root motion or stiff aortas.
Pagoulatou et al. (2020) studied this question.
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