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A depressive syndrome, closely resembling melancholia, was found in a large proportion of chronic schizophrenic men. Depression was most prominent during acute psychotic phases and was characterized by a delusional core of worthlessness and guilt. The depressive syndrome may persist throughout the patient's psychotic life and appears to be an integral component of schizophrenic psychopathology.
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Planansky et al. (1978) studied this question.
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