The H-Y Antigen and Male Sexual Development

The aberrations of the male gonads and genitalia range from such common entities as hypospadias and undescended testes to rare and bizarre disorders like hermaphroditism. As is often the case, the cause of the more common disorders has proved to be elusive, but some insight into the rarer entities is being attained from studies of the H-Y antigen. A case in point is the study by Winters and his colleagues in this issue of the Journal. Cases of this kind are worthy of close observation in the hope that the resolution of the rare end of the spectrum of . . .