Why the study?
Do leukocyte count and aggregation correlate with the severity of cerebral ischemic injury in patients with atherothrombotic stroke or transient ischemic attacks?
Do leukocyte count and aggregation correlate with the severity of cerebral ischemic injury in patients with atherothrombotic stroke or transient ischemic attacks?
Leukocyte aggregation, but not leukocyte count, correlates with the severity of neurological impairment in patients with atherothrombotic stroke, suggesting a role for altered leukocyte rheology in cerebral ischemic injury.
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Leukocyte aggregation may mark greater stroke severity; hypothesis-generating and requires prospective validation before clinical consideration.
Silvestrini et al. (1998) studied this question.